AI Digital Precision Healthcare Program Director, Commercial Digital Health

Location: Gaithersburg

As AI Digital Precision Healthcare Program Lead, you will be responsible for driving the design, execution, development, and scaling of cutting‑edge, AI‑enabled programs that optimize the oncology care pathway, from early patient identification and diagnosis to clinical development acceleration and the adoption of innovative medicines.

You will act as the primary liaison between internal sponsors (Commercial, Medical, R&D, Market Access, and Diagnostics) and external partners co‑developing clinical decision support (CDS) and AI‑based care optimization solutions. Your mission is to leverage data, technology, and scientific excellence to close key gaps in patient care and create measurable clinical and business value across the ecosystem, ensuring that impactful solutions are not only created but also successfully scaled across markets and therapeutic areas.

This position will work in close collaboration with the Value‑Based Partnership team, ensuring the identification, evaluation, and integration of external partners specialized in AI‑driven clinical decision tools and health data platforms, while building the capabilities, operating models, and governance structures required to develop, operationalize, and scale high‑value innovations globally.

Key responsibilities include:

1. Strategic and Scientific Leadership

• Define and prioritize business needs with internal stakeholders
• Define, prioritize, and lead the design and execution of AI-based clinical decision support solutions addressing key care pathway needs.
• Act as product owner for assigned initiatives, translating business objectives into scientifically sound methodologies and data-driven tools.
• Design and deliver innovative solutions that:

• Support physicians in diagnosis, treatment selection, and adoption of innovative medicines.
• Optimize the patient journey through activation and personalized support tools.
• Strengthen AstraZeneca’s capacity in AI-based precision medicine and health data utilization.

2. External Partnership Development

• In collaboration with the Value-Based Partnership team, identify and engage with digital health and precision medicine vendors offering unique capabilities in CDS and data analytics.
• Critically evaluate partner methodologies, providing scientific and strategic input to ensure innovation, compliance, and impact alignment.
• Integrate external insights with internal priorities to ensure co-created, high-value outcomes.

3. Internal Cross-Functional Collaboration

• Coordinate multi-stakeholder collaborations across Commercial, Medical, R&D, Market Access, and Diagnostics to analyze business opportunities and deploy solutions regionally or globally.
• Build strong relationships with business owners and maintain transparent communication on program strategy, milestones, and results.
• Align projects with therapeutic and regional strategies, ensuring compliance with local regulatory and operational frameworks.

4. Program Execution and Governance

• Oversee the full lifecycle of assigned programs, from initiation to delivery and impact assessment.
• Manage program budgets, contracts, and cross-functional processes in collaboration with Legal, Compliance, Procurement, and IP teams.
• Track operational performance, risks, and opportunities to ensure timely delivery and measurable outcomes.
• Define and ensure adherence to data, digital, and regulatory frameworks governing project execution.

5. Leadership and Capability Building

• Contribute to the development and mentorship of the Digital Healthcare Delivery team by sharing expertise in precision medicine, AI-enabled CDS tools, and digital biomarkers.
• Foster internal and external collaborations with commercial, R&D, and market access teams, key markets, external experts, and patient communities to ensure that initiatives address prioritized unmet needs.

Initial Focus and Expected Outcomes

• Partner with business owners to identify and create data- and AI-driven value propositions aligned with oncology strategic priorities.
• Launch and manage high-impact AI care pathway optimization programs, ensuring measurable value delivery across therapeutic areas and geographies.
• Collaborate across clinical, commercial, and market access functions to accelerate the adoption of innovative medicines in local markets.
• Contribute to the personal development of the Digital Healthcare Delivery team members. Providing expert advice on strategic and innovative precision medicine approaches, or AI embedded clinical decision tools to regional leads.
• Grow and maintain internal and external collaborations commercial organisation and R&D, key markets, external leaders and our patients to ensure prioritised needs are met in everything we do.

Essential requirements 

• Advanced degree (Master’s or PhD) in a relevant field such as Biomedical Engineering, Data Science, Computational Biology, Bioinformatics, Digital Health, or Artificial Intelligence.  
• + 5 years of experience in digital healthcare project management
• Track record in developing and deploying impactful healthcare digital program
• Very good understanding information systems such as Electronic Medical Record, Clinical Trial Management, and Electronic Data Capture platforms.
• Strong communication and organizational skills
• Detail oriented, and enjoy a highly collaborative working relationship that encourages sharing
• Proven experience in partnering and unlocking access to novel data partnerships
• Understanding of the rapidly changing external environment including new innovative digital technology innovations
• Highly developed communication and influencing abilities across organizational teams and levels in a large complex operating environment
• Results driven approach to work and project development
• Ability to express complex ideas in clear and compelling way to multiple external and internal stakeholder groups
• Entrepreneurial with the highest level of integrity and the ability to foster trust and loyalty
• Motivated by delivering digital innovation in service of enhanced patient outcomes and treatment experience
  

Desirable requirements:

• Experience on bringing innovation that is solving complex and multi-dimensional issues from an operational, technical, financial and human perspective
• Strong knowledge of International ecosystem (key stakeholders, healthcare system, actors, payers, compliance, start-up/tech partners environment)
• Experience in driving global change in complex organisations, covering multiple cultures and significant number of functions
• Ability to work with all stakeholders to identify their requirements:
  • Medical / Scientific knowledge in Oncology / Biopharma
  • Good knowledge in Market Access (Value Based Healthcare,
  • Good knowledge on Clinical Trials (Design & Solutions)
  • Knowledge in compliance / Legal (Medical device, Data)
    

When we put unexpected teams in the same room, we foster bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.   

The annual base pay (or hourly rate of compensation) for this position ranges from $157 440,00 - $ 236 160, either as annual base pay or as the hourly rate (annual base pay divided by 2080 hours)]. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​